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Rabbit Anti-IOC4/AP Conjugated antibody (bs-18181R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18181R-AP
英文名稱 Rabbit Anti-IOC4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的IOC4
別    名 Hypothetical 55.4 kDa protein in MCM1-NUP116 intergenic region; Ioc4p; IOC4_YEAST; YMR044W.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae IOC4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
IOC4 is a member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing. IOC4 contains a PWWP motif.

Function:
Functions as component of the ISW1B complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing.

Subunit:
Component of the ISW1B complex, which at least consists of ISW1, IOC2 and IOC4.

Subcellular Location:
Nuclear

Database links:

Entrez Gene: 855061 Saccharomyces cerevisiae

SwissProt: Q04213 Saccharomyces cerevisiae



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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