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Rabbit Anti-TAS2R49/Gold Conjugated antibody (bs-11789R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11789R-Gold
英文名稱 Rabbit Anti-TAS2R49/Gold Conjugated antibody
中文名稱 膠體金標記的味覺2型受體蛋白家族49抗體
別    名 T2R20; T2R20_HUMAN; T2R49; T2R56; TAS2R20; Taste receptor type 2 member 20; Taste receptor type 2 member 49; Taste receptor type 2 member 56  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  神經生物學  信號轉導  通道蛋白  細胞膜受體  G蛋白偶聯受體  G蛋白信號  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TAS2R49
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. T2R49 plays a role in sensing the chemical composition of the gastrointestinal content. T2R49 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Function:
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Similarity:
Belongs to the G-protein coupled receptor T2R family.

Database links:
UniProtKB/Swiss-Prot: P59543.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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