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Rabbit Anti-NAP1L1/Gold Conjugated antibody (bs-1052R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-1052R-Gold
英文名稱 Rabbit Anti-NAP1L1/Gold Conjugated antibody
中文名稱 膠體金標記的核小體組裝蛋白1抗體
別    名 NAP1L; FLJ16112; hNRP; HSP22 like protein interacting protein; MGC23410; MGC8688; NAP 1; NAP 1 related protein; NAP 1L; NAP-1 related protein; NAP-1-related protein; NAP1; NAP1 L1; NAP1 related protein; Nap1l1; NAP1L1 protein; NP1L1_HUMAN; NRP; Nucleosome assembly protein 1 like 1; Nucleosome assembly protein 1-like 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 染色質和核信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAP1L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. The binding of sequence-specific DNA binding proteins to human nucleosome assembly protein 1 may be an important step contributing to the activation of transcription. May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Function:
May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Subcellular Location:
Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
Polyglutamylated by TTLL4, a modification that occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Some residues may also be monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:

Entrez Gene: 4673 Human

Entrez Gene: 53605 Mouse

Entrez Gene: 89825 Rat

Omim: 164060 Human

SwissProt: P55209 Human

SwissProt: P28656 Mouse

SwissProt: Q9Z2G8 Rat

Unigene: 524599 Human

Unigene: 695185 Human

Unigene: 290407 Mouse

Unigene: 162938 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

核小體組裝蛋白1(NAP-1) 作為核心組蛋白的分子伴蛋白,在進化過程中是相當保守的.它通過幫助核心組蛋白沉積到DNA上來促進核小體的組裝.而大量研究表明,酵母和動物中的NAP類似蛋白除了具有核小體組裝能力以外,還有其它多種功能
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