| 產(chǎn)品編號(hào) | IHC0429 |
| 英文名稱(chēng) | TARDBP Ready-To-Use IHC Kit |
| 中文名稱(chēng) | Tar DNA 結(jié)合蛋白43即用型免疫組化試劑盒 |
| 別 名 | 1190002A23Rik; ALS10; C85084; TARDBP; TDP-43; TDP43; wu:fb77f02; wu:fc52g10 |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences. SWISS: Q13148 Gene ID: 23435 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse brain tissue slide using IHC0429 (TARDBP IHC Kit).
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Immunohistochemical analysis of paraffin embedded mouse colon tissue slide using IHC0429 (TARDBP IHC Kit).
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0429 (TARDBP IHC Kit).
腸.jpg)
Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0429 (TARDBP IHC Kit).
Immunohistochemical analysis of paraffin embedded rat brain tissue slide using IHC0429 (TARDBP IHC Kit).
腸.jpg)
Immunohistochemical analysis of paraffin embedded rat colon tissue slide using IHC0429 (TARDBP IHC Kit).
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