產(chǎn)品編號 | IHC0398H |
英文名稱 | Human IRF4 Ready-To-Use IHC Kit |
中文名稱 | 人干擾素調(diào)節(jié)因子4即用型免疫組化試劑盒 |
別 名 | AI385587; IRF-4; IRF4; LSIRF; MUM1; NF-EM5; SHEP8; Spip |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found. SWISS: Q15306 Gene ID: 3662 |
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