| 產(chǎn)品編號(hào) | bsm-10818M |
| 英文名稱 | AD7c-NTP Mouse mAb |
| 中文名稱 | 神經(jīng)絲蛋白單克隆抗體 |
| 別 名 | neuronal thread protein AD7c-NTP; AD7c-NTP. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | 2F5 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant human AD7C NTP full length protein |
| 亞 型 | IgG1 |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease. Gene ID: AD7c Database links: GenBank: AAC08737 AD7C-NTP是存在于神經(jīng)元中的一種41Kda的蛋白質(zhì)，在AD患者腦內(nèi)選擇性升高，和其病理過程相關(guān)，AD7C-NTP基因也只在神經(jīng)元表達(dá)，AD患者腦脊液中AD7C-NTP表達(dá)升高， AD7C-NTP作為AD早期診斷和確診的生物化學(xué)標(biāo)志正引起越來越多的關(guān)注. |
