| 產品編號 | bs-19753R |
| 英文名稱 | SH3D20 Rabbit pAb |
| 中文名稱 | SH3結構域結合蛋白D20抗體 |
| 別 名 | ARHGAP27; CAMGAP1; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; PP905; RHG27_HUMAN; Rho GTPase-activating protein 27; Rho-type GTPase-activating protein 27; SH3 domain containing 20; SH3 domain containing protein 20; SH3D20; S |
| 研究領域 | 腫瘤 細胞生物 信號轉導 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse) |
| 產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 98 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SH3D20: 531-630/889 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013] Function: Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1. Subcellular Location: Cytoplasm. Membrane. Tissue Specificity: Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer. Similarity: Contains 1 PH domain. Contains 1 Rho-GAP domain. Contains 1 SH3 domain. Contains 3 WW domains. SWISS: Q6ZUM4 Gene ID: 201176 Database links: Entrez Gene: 201176 Human Entrez Gene: 544817 Mouse Omim: 610591 Human SwissProt: Q6ZUM4 Human SwissProt: A2AB59 Mouse Unigene: 205326 Human Unigene: 397197 Mouse Unigene: 17895 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
