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EML2 Rabbit pAb (bs-20006R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-20006R
英文名稱 EML2 Rabbit pAb
中文名稱 EML2蛋白抗體
別    名 1600029N02Rik; Echinoderm microtubule associated protein like 2; Echinoderm microtubule-associated protein-like 2; Echinoderm MT associated protein like protein 70; ELP70; EMAL2_HUMAN; EMAP-2; EMAP2; EML2; HuEMAP-2.  
研究領域 細胞生物  神經生物學  信號轉導  細胞凋亡  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 71 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EML2: 561-649/649 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Microtubules are components of the actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML2 (echinoderm microtubule associated protein like 2), also known as ELP70, EMAP2 or EMAPL2, is a cytoplasmic protein that acts to elongate microtubules, while at the same time making them more dynamic. Like other members of the EML family, EML2 contains a hydrophobic ELP (HELP) domain and a large WD repeat domain, both of which allow EML2 to participate in cytoskeleton assembly.

Function:
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

Subcellular Location:
Cytoplasm; cytoskeleton.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the WD repeat EMAP family.
Contains 11 WD repeats.

SWISS:
O95834

Gene ID:
24139

Database links:

Entrez Gene: 24139 Human

Entrez Gene: 72205 Mouse

Entrez Gene: 192360 Rat

SwissProt: O95834 Human

SwissProt: Q7TNG5 Mouse

SwissProt: Q6P6T4 Rat

Unigene: 24178 Human

Unigene: 154121 Mouse

Unigene: 76362 Rat



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