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HLF Rabbit pAb (bs-18045R)  
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50ul/1180.00元
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產品編號 bs-18045R
英文名稱 HLF Rabbit pAb
中文名稱 白血病抑制因子抗體
別    名 Hepatic leukemia factor; Hlf; HLF/E2A FUSION GENE; HLF_HUMAN.  
研究領域 腫瘤  細胞生物  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Cow,Horse)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HLF: 201-295/295 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Function:
Highly expressed in liver; lower levels in lung and kidney.

Subcellular Location:
Nucleus.

DISEASE:
Note=A chromosomal aberration involving HLF is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Translocation t(17;19)(q22;p13.3) with TCF3.

Similarity:
Belongs to the bZIP family. PAR subfamily.
Contains 1 bZIP domain.

SWISS:
Q16534

Gene ID:
3131

Database links:

Entrez Gene: 3131 Human

Entrez Gene: 217082 Mouse

Entrez Gene: 363667 Rat

Omim: 142385 Human

SwissProt: Q16534 Human

SwissProt: Q8BW74 Mouse

SwissProt: Q64709 Rat

Unigene: 196952 Human

Unigene: 158903 Mouse



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