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HSD17B7 Rabbit pAb (bs-16528R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-16528R
英文名稱 HSD17B7 Rabbit pAb
中文名稱 17β羥類固醇脫氫酶7抗體
別    名 17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto steroid reductase; 3-keto-steroid reductase; DHB7_HUMAN; Estradiol 17 beta dehydrogenase 7; Estradiol 17-beta-dehydrogenase 7; Hsd17b7; hydroxysteroid(17 beta) dehydrogenase 7; MGC12523; MGC75018; PRAP; SDR37C1; Short chain dehydrogenase/reductase family 37C member 1.  
研究領域 腫瘤  細胞生物  信號轉導  新陳代謝  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSD17B7: 31-130/341 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]

Function:
Responsible for the reduction of the keto group on the C-3 of sterols.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

SWISS:
P56937

Gene ID:
51478

Database links:

Entrez Gene: 51478 Human

Entrez Gene: 15490 Mouse

Entrez Gene: 29540 Rat

Omim: 606756 Human

SwissProt: P56937 Human

SwissProt: O88736 Mouse

SwissProt: Q62904 Rat

Unigene: 492925 Human

Unigene: 12882 Mouse

Unigene: 7040 Rat



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