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DDX6 Rabbit pAb (bs-14239R)  
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產品編號 bs-14239R
英文名稱 DDX6 Rabbit pAb
中文名稱 ATP依賴RNA解旋酶DDX6抗體
別    名 ATP dependent RNA helicase DDX6; ATP dependent RNA helicase p54; DDX6; DEAD(Asp Glu Ala Asp) box polypeptide 6; DEAD box 6; DEAD box protein 6; DEAD/H(Asp Glu Ala Asp/His) box polypeptide 6(RNA helicase 54kD); FLJ36338; HLR2; Oncogene RCK; P54; Probable A  
Specific References  (1)     |     bs-14239R has been referenced in 1 publications.
[IF=5.051] Du Zhi. et al. Circulating exosomal circRNA_0063476 impairs expression of markers of bone growth via the miR-518c-3p/DDX6 axis in ISS. ENDOCRINOLOGY. 2022 Aug;:  IHC ;  Rat.  
研究領域 細胞凋亡  轉錄調節因子  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 54 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX6: 51-150/483 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012]

Function:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis and cellular growth and division. In the process of mRNA degradation, DDX6 may play a role in mRNA decapping. It forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS.

Subcellular Location:
Cytoplasm; P-body. Note: Processing bodies (PB).

SWISS:
P26196

Gene ID:
1656

Database links:

Entrez Gene: 1656 Human

Entrez Gene: 13209 Mouse

Entrez Gene: 500988 Rat

Omim: 600326 Human

SwissProt: P26196 Human

SwissProt: P54823 Mouse

Unigene: 408461 Human

Unigene: 267061 Mouse



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