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SLC34A2 Rabbit pAb (bs-0856R)  
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50ul/1180.00元
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產品編號 bs-0856R
英文名稱 SLC34A2 Rabbit pAb
中文名稱 磷酸鈉協同轉運蛋白抗體
別    名 NaPi-2b; Sodium-dependent phosphate transport protein 2B; Sodium/phosphatecotransporter 2B; Na(+)/Pi cotransporter 2B; Sodium-phosphatetransport protein 2B; Na(+)-dependent phosphate cotransporter 2B; Solute carrier family 34 member 2; NPT2B_HUMAN; NaPi3b  
研究領域 細胞生物  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse,Rat)
產品應用 WB=1:500-2000,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 77 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SLC34A2: 1-50/697 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Na+/Pi-cotransporterThis is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows reabsorption of filtered Pi in the proximal tubule.

Function:
May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Highly abundant in the ileum of small intestine, whereas it is almost absent in the duodenum and in the jejunum.

Similarity:
Belongs to the SLC34A transporter family.

Gene ID:
20531

Database links:

Entrez Gene: 10568 Human

Entrez Gene: 20531 Mouse

Omim: 604217 Human

SwissProt: O95436 Human

Unigene: 479372 Human



SLC34A2/NaPi-2b是磷酸鈉協同轉運蛋白的基因,表達在動物多種組織中,以肺組織表達最高。該基因主要參與無機磷代謝,與肺泡微石癥、睪丸微石癥等多種代謝性疾病發病相關。
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